Latest episode:
#517 Agentic Al Programming with Python
Agentic AI programming is what happens when coding assistants stop acting like autocomplete and start collaborating on real work. In this episode, we cut through the hype and incentives to define “agentic,” then get hands-on with how tools like Cursor, Claude Code, and LangChain actually behave inside an established codebase. Our guest, Matt Makai, now VP of Developer Relations at DigitalOcean, creator of Full Stack Python and Plushcap, shares hard-won tactics. We unpack what breaks, from brittle “generate a bunch of tests” requests to agents amplifying technical debt and uneven design patterns. Plus, we also discuss a sane git workflow for AI-sized diffs. You’ll hear practical Claude tips, why developers write more bugs when typing less, and where open source agents are headed. Hint: The destination is humans as editors of systems, not just typists of code.
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Beginners
Effective PyCharm
HMTX + Flask
Upcoming episodes
Twenty years after a scrappy newsroom team hacked together a framework to ship stories fast, Django remains the Python web framework that ships real apps, responsibly. In this anniversary roundtable with its creators and long-time stewards: Simon Willison, Adrian Holovaty, Will Vincent, Jeff Triplet, and Thibaud Colas, we trace the path from the Lawrence Journal-World to 1.0, DjangoCon, and the DSF; unpack how a BSD license and a culture of docs, tests, and mentorship grew a global community; and revisit lessons from deployments like Instagram. We talk modern Django too: ASGI and async, HTMX-friendly patterns, building APIs with DRF and Django Ninja, and how Django pairs with React and serverless without losing its batteries-included soul. You’ll hear about Django Girls, Djangonauts, and the Django Fellowship that keep momentum going, plus where Django fits in today’s AI stacks. Finally, we look ahead at the next decade of speed, security, and sustainability.
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Consistently excellent content and great guestsMichael is one of the leading voices of the Python community. The content is always intriguing and a great way to stay motivated while learning. Keep up the great work!
Every time I learn something newEvery time I listen to a Michael Kennedy Podcast, I learn something new. It’s so educational just hearing the interviews. Genuinely going in depth about different subjects in the world of coding - from a Python perspective. Great guest! So much insight. 💙
Finance - risk guyHey, I'm a finance and risk guy that is newer to Python, was using excel vba macros but once I saw the power and possibilities of Python, have been hooked ever since. Love the podcast, I think I am a wannabe developer, maybe some day, haha. Take it easy.
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More about Talk Python to Me
Talk Python to Me is a weekly podcast hosted by
Michael Kennedy.
The show covers a wide array of Python topics as well as
many related topics.
The format is a casual 1-hour conversation with industry
experts.
Have feedback for the show? Send it to
contact@talkpython.fm.
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Do you have a great idea for a show? Do know a dynamic Python
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