Today we’re turning tiny tips into big wins. Khuyen Tran, creator of CodeCut.ai, has shipped hundreds of bite-size Python and data science snippets across four years. We dig into open-source tools you can use right now, cleaner workflows, and why notebooks and scripts don’t have to be enemies. If you want faster insights with fewer yak-shaves, this one’s packed with takeaways you can apply before lunch. Let’s get into it.
Full details »
Python typing got fast enough to feel invisible. Pyrefly is a new, open source type checker and IDE language server from Meta, written in Rust, with a focus on instant feedback and real-world DX. Today, we will dig into what it is, why it exists, and how it plays with the rest of the typing ecosystem. We have Abby Mitchell, Danny Yang, and Kyle Into from Pyrefly here to dive into the project.
Python in 2025 is different. Threads really are about to run in parallel, installs finish before your coffee cools, and containers are the default. In this episode, we count down 38 things to learn this year: free-threaded CPython, uv for packaging, Docker and Compose, Kubernetes with Tilt, DuckDB and Arrow, PyScript at the edge, plus MCP for sane AI workflows. Expect practical wins and migration paths. No buzzword bingo, just what pays off in real apps. Join me along with Peter Wang and Calvin Hendrix-Parker for a fun, fast-moving conversation.
Building a UI in Python usually means choosing between "quick and limited" or "powerful and painful." What if you could write modern, component-based web apps in pure Python and still keep full control? NiceGUI, pronounced "Nice Guy" sits on FastAPI with a Vue/Quasar front end, gives you real components, live updates over websockets, and it’s running in production at Zauberzeug, a German robotic company. On this episode, I’m talking with NiceGUI’s creators, Rodja Trappe and Falko Schindler, about how it works, where it shines, and what’s coming next. With version 3.0 releasing around the same time this episode comes out, we spend the end of the episode celebrating the 3.0 release.
Every time I learn something newEvery time I listen to a Michael Kennedy Podcast, I learn something new. It’s so educational just hearing the interviews. Genuinely going in depth about different subjects in the world of coding - from a Python perspective. Great guest! So much insight. 💙
Lots of great interviewsIt has inspiring content, awesome interviews, and explores the vastness of the Python community.
Love this showI get sad after listening to every new episode because I have to wait for the next one.
Talk Python to Me is a weekly podcast hosted by
Michael Kennedy.
The show covers a wide array of Python topics as well as
many related topics.
The format is a casual 1-hour conversation with industry
experts.
Have feedback for the show? Send it to
contact@talkpython.fm.
We'd love to hear from you.
We are always on the look out for exciting topics to bring
to you on Talk Python To Me. We could use your help!
Do you have a great idea for a show? Do know a dynamic Python
personality who we should be speaking to? Send us an email!